MEAI (also known as 5-Methoxy-2-Aminoindane, 5-MeO-AI, or CMND-100) is a synthetic aminoindane derivative belonging to the phenethylamine family of research compounds. Due to its unique pharmacological profile and growing scientific interest, MEAI has become an important analytical reference standard in medicinal chemistry, neuropharmacology, forensic toxicology, and analytical laboratories.
With its well-characterized molecular structure and emerging relevance in pharmaceutical research, MEAI is widely utilized in analytical method development, drug metabolism investigations, pharmacological studies, forensic identification, and structure–activity relationship (SAR) research.
MEAI is supplied strictly for laboratory, analytical, and scientific research purposes only. It is not approved for human or veterinary use.
What is MEAI?
MEAI is a synthetic aminoindane compound and the 5-methoxy analogue of 2-aminoindane. It has attracted considerable scientific interest due to its interaction with monoamine neurotransmitter systems and its investigation as a potential candidate for neurological and behavioral research.
Research laboratories utilize MEAI as a certified analytical reference material to support pharmacological investigations, forensic screening, analytical method validation, metabolite identification, and structure–activity relationship (SAR) research.
Chemical Structure and Properties
MEAI possesses several analytical characteristics valuable for laboratory research:
- Aminoindane core structure
- Methoxy-substituted aromatic ring
- High analytical stability
- Well-defined chromatographic behavior
- Excellent compatibility with LC-MS/MS and GC-MS instrumentation
- Suitable for analytical reference library development
- Reliable forensic identification marker
These characteristics enable reproducible laboratory analyses and accurate analytical identification across modern analytical platforms.
Scientific Research Applications
MEAI is widely employed in:
- Analytical chemistry
- Medicinal chemistry
- Neuropharmacology research
- Drug metabolism investigations
- Forensic toxicology
- Toxicological screening
- Pharmaceutical analytical research
- Academic research
- Novel psychoactive substance (NPS) monitoring
- Reference standard development
Analytical Applications
Professional laboratories commonly use MEAI for:
- LC-MS/MS calibration
- GC-MS identification
- LC-HRMS analysis
- HPLC method validation
- Analytical method development
- Forensic drug screening
- Quality assurance testing
- Metabolite profiling
- Toxicology reference library creation
Its consistent analytical performance makes it valuable for modern forensic and pharmaceutical laboratories.
Pharmacology Research
Researchers investigate MEAI in studies involving:
- Monoamine transporter research
- Serotonin transporter (SERT) characterization
- Norepinephrine transporter (NET) studies
- Structure–activity relationship (SAR) analysis
- Drug metabolism and biotransformation
- Neuropharmacology
- Medicinal chemistry
- Analytical toxicology
- Emerging aminoindane research
These investigations contribute to advancements in analytical science and pharmaceutical research.
Why Researchers Choose MEAI
Researchers select MEAI because it provides:
- High analytical purity
- Well-characterized molecular structure
- Stable chromatographic behavior
- Excellent mass spectrometric response
- Significant forensic relevance
- Reliable analytical reference capabilities
- Broad applicability in toxicology laboratories
Related Research Compounds
Researchers frequently compare MEAI with related compounds including:
- MDAI
- MMAI
- 2-AI
- MDMA
- MDA
- 3-Methoxyamphetamine (3-MA)
- Amphetamine
- 5-MeO-DiPT
- 5-MeO-DMT
- Methylone
Comparative studies support analytical identification, metabolism research, and structure–activity relationship investigations.
Storage and Handling
For optimal laboratory stability:
- Store in airtight laboratory containers.
- Protect from heat, moisture, and direct sunlight.
- Maintain storage in a cool, dry environment.
- Handle using appropriate laboratory personal protective equipment (PPE).
- Follow institutional laboratory safety procedures.
Frequently Asked Questions
What is MEAI?
MEAI is a synthetic aminoindane compound used as an analytical reference standard in forensic toxicology, medicinal chemistry, analytical chemistry, and neuropharmacology research.
Which laboratories use MEAI?
It is commonly used by forensic laboratories, toxicology laboratories, pharmaceutical researchers, academic institutions, and analytical chemistry laboratories.
Which analytical techniques are commonly used?
Researchers commonly analyze MEAI using LC-MS/MS, GC-MS, LC-HRMS, HPLC, and related analytical techniques.
Why is MEAI valuable in research?
Its well-characterized molecular profile, analytical stability, and pharmacological relevance make it valuable for method validation, metabolite identification, and analytical reference development.
Is MEAI intended only for research?
Yes. MEAI is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.
Disclaimer
MEAI is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary applications, therapeutic use, or diagnostic procedures. Users are responsible for complying with all applicable local laws, institutional policies, and laboratory safety regulations.
