5F-UR144, also known as XLR-11 or 5-Fluoro UR-144, is a synthetic cannabinoid research chemical belonging to the tetramethylcyclopropylindole class of novel psychoactive substances (NPS). It is structurally derived from UR-144 through the addition of a fluorinated pentyl side chain, making it an important compound for analytical chemistry, forensic toxicology, and cannabinoid receptor research.
Today, 5F-UR144 is widely utilized as an analytical reference standard for laboratory identification, method validation, and scientific investigations involving synthetic cannabinoids.
What is 5F-UR144?
5F-UR144 is an indole-based synthetic cannabinoid developed for scientific investigations involving cannabinoid receptor pharmacology and forensic identification. The compound serves as an important analytical standard for laboratories studying emerging synthetic cannabinoids and developing reliable analytical detection methods.
Its fluorinated molecular structure makes it valuable for comparative studies involving cannabinoid analogues and receptor-binding research.
Chemical Structure and Properties
5F-UR144 possesses several notable structural characteristics:
- Indole core structure
- Tetramethylcyclopropyl ketone group
- Fluorinated pentyl side chain
- Lipophilic aromatic framework
- High chemical stability under laboratory storage conditions
These structural features contribute to its importance in analytical chemistry and medicinal chemistry research.
Scientific Importance
Researchers utilize 5F-UR144 in numerous scientific disciplines, including:
- Cannabinoid receptor studies
- Synthetic cannabinoid profiling
- Medicinal chemistry
- Structure-activity relationship (SAR) analysis
- Pharmaceutical research
- Analytical chemistry
- Forensic toxicology
- Novel psychoactive substance monitoring
Its molecular profile provides valuable insight into the development and characterization of synthetic cannabinoid compounds.
Analytical Applications
5F-UR144 is commonly employed in laboratory workflows such as:
- LC-MS/MS analysis
- GC-MS identification
- High-resolution mass spectrometry (HRMS)
- Analytical method validation
- Reference standard calibration
- Laboratory quality assurance
- Forensic sample comparison
- Chemical identification studies
These applications enable laboratories to accurately detect and differentiate synthetic cannabinoid compounds.
Why Researchers Study 5F-UR144
Current research involving 5F-UR144 focuses on:
- Cannabinoid receptor interaction studies
- Forensic toxicology investigations
- Emerging NPS identification
- Pharmaceutical compound evaluation
- Analytical reference development
- Medicinal chemistry research
- Laboratory method optimization
Its unique fluorinated structure makes it an important reference material for analytical and forensic laboratories worldwide.
Related Research Compounds
Researchers frequently compare 5F-UR144 with:
- UR-144
- XLR-11
- 5F-AKB48
- 5F-ADB
- 4F-ADB
- AM-2201
- JWH-018
- Other synthetic cannabinoids
Comparative analysis assists in structural characterization and analytical differentiation.
Research Applications
Potential laboratory applications include:
- Analytical chemistry
- Forensic toxicology
- Pharmaceutical development
- Cannabinoid receptor research
- Scientific reference standards
- Laboratory calibration
- Academic research
- Chemical identification
Storage and Handling
For maximum product stability:
- Store in airtight laboratory containers.
- Keep in a cool, dry environment.
- Protect from direct sunlight.
- Avoid excessive heat and moisture.
- Use appropriate laboratory personal protective equipment (PPE).
- Follow institutional laboratory safety protocols during handling.
Frequently Asked Questions
What is 5F-UR144?
5F-UR144 is an indole-based synthetic cannabinoid research chemical primarily used in analytical chemistry, forensic toxicology, and cannabinoid receptor research.
What is the molecular formula of 5F-UR144?
The molecular formula is C₂₁H₂₈FNO.
What is XLR-11?
XLR-11 is one of the most commonly used alternative names for 5F-UR144.
What research fields utilize 5F-UR144?
It is widely used in forensic toxicology, analytical chemistry, pharmaceutical research, medicinal chemistry, and cannabinoid receptor investigations.
Why is 5F-UR144 valuable for laboratories?
It serves as an analytical reference standard for identifying synthetic cannabinoids, validating laboratory methods, and supporting forensic investigations.
Is this product intended for laboratory research only?
Yes. This material is supplied exclusively for scientific, analytical, educational, and laboratory research purposes.
Disclaimer
This product is intended solely for laboratory, scientific, analytical, and educational research. It is not intended for human consumption, medical treatment, veterinary applications, or therapeutic use. Researchers are responsible for complying with all applicable regulations, laboratory safety requirements, and institutional guidelines.
