CUMYL-PINACA, also known as SGT-24, is a high-purity indazole-3-carboxamide analytical reference standard widely utilized in forensic toxicology, analytical chemistry, medicinal chemistry, pharmaceutical research, and cannabinoid receptor studies. Originally developed during cannabinoid research programs, CUMYL-PINACA has become an important reference material for laboratories investigating synthetic cannabinoid chemistry, receptor pharmacology, metabolism, and analytical detection.
Today, CUMYL-PINACA is supplied exclusively for scientific, analytical, forensic, and laboratory research.
What is CUMYL-PINACA?
CUMYL-PINACA is a synthetic cannabinoid developed during research into cannabinoid receptor ligands. It belongs to the indazole-3-carboxamide family and serves as a valuable analytical reference compound for studying cannabinoid receptor interactions, metabolic pathways, and analytical identification.
Its well-characterized molecular structure makes it useful for forensic investigations and medicinal chemistry research involving synthetic cannabinoid analogues.
Chemical Structure and Properties
CUMYL-PINACA contains several defining structural features:
- Indazole core
- Carboxamide linkage
- Cumyl (2-phenylpropan-2-yl) substituent
- Pentyl side chain
- High chemical stability
- Hydrophobic molecular profile
These characteristics support reproducible chromatographic behavior and reliable analytical identification.
Pharmacological Research
Experimental studies have shown that CUMYL-PINACA interacts with cannabinoid CB₁ and CB₂ receptors, making it an important research compound for investigations into cannabinoid receptor pharmacology.
Current scientific research includes:
- Cannabinoid receptor binding studies
- CB₁ receptor pharmacology
- CB₂ receptor investigations
- Ligand–receptor interaction research
- Neuropharmacology
- Structure–activity relationship (SAR) analysis
- Medicinal chemistry optimization
- Drug metabolism research
These investigations contribute to a broader understanding of synthetic cannabinoid receptor ligands and their biochemical properties.
Scientific Research Applications
CUMYL-PINACA is widely used in:
- Forensic toxicology laboratories
- Pharmaceutical research
- Medicinal chemistry programs
- Academic neuroscience
- Analytical chemistry laboratories
- Drug metabolism studies
- Quality control laboratories
- Reference standard production
- Cannabinoid pharmacology research
Analytical Applications
Professional laboratories utilize CUMYL-PINACA for:
- LC-MS/MS calibration
- GC-MS analysis
- HPLC method development
- High-Resolution Mass Spectrometry (HRMS)
- Toxicology screening
- Method validation
- Quality assurance testing
- Analytical reference library development
Its well-defined analytical profile enables accurate identification and differentiation from structurally related synthetic cannabinoids.
Why Researchers Choose CUMYL-PINACA
Researchers select CUMYL-PINACA because it offers:
- Well-characterized molecular structure
- High analytical purity
- Reliable laboratory performance
- Consistent chromatographic properties
- Valuable cannabinoid receptor research model
- Broad forensic applications
- Excellent SAR comparison with related cannabinoid analogues
These qualities make it a valuable analytical reference standard across multiple research disciplines.
Related Research Compounds
Researchers frequently compare CUMYL-PINACA with:
- 5F-CUMYL-PINACA
- AB-PINACA
- ADB-PINACA
- AB-FUBINACA
- ADB-FUBINACA
- CUMYL-INACA
- MDMB-PINACA derivatives
- Other indazole-based synthetic cannabinoids
Comparative studies improve understanding of receptor binding, metabolism, analytical detection, and molecular structure within the synthetic cannabinoid class.
Storage and Handling
For optimal laboratory stability:
- Store in airtight laboratory containers.
- Protect from moisture and humidity.
- Avoid prolonged exposure to light.
- Maintain recommended laboratory storage temperatures.
- Handle using appropriate laboratory PPE.
- Follow institutional laboratory safety procedures.
Frequently Asked Questions
What is CUMYL-PINACA?
CUMYL-PINACA (SGT-24) is an indazole-based synthetic cannabinoid analytical reference standard used in forensic toxicology, medicinal chemistry, cannabinoid receptor research, and analytical chemistry.
Which laboratories use CUMYL-PINACA?
It is commonly used by forensic laboratories, pharmaceutical researchers, academic institutions, medicinal chemists, analytical chemistry laboratories, and toxicology facilities.
Which analytical techniques are suitable for CUMYL-PINACA?
Researchers commonly analyze CUMYL-PINACA using LC-MS/MS, GC-MS, HPLC, and HRMS for compound identification, calibration, quality assurance, and analytical method validation.
Why is CUMYL-PINACA important in research?
Its defined chemical structure, cannabinoid receptor interaction profile, and analytical consistency make it valuable for pharmacological investigations, forensic studies, and medicinal chemistry research.
Is CUMYL-PINA
PINACA intended only for research?
Yes. This product is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.
Disclaimer
CUMYL-PINACA is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary use, therapeutic applications, or diagnostic purposes. Researchers are responsible for ensuring compliance with all applicable laws, institutional policies, and laboratory safety regulations.
