GHV (γ-Hydroxyvaleric Acid), also known as 4-Methyl GHB, is a synthetic hydroxy acid belonging to the gamma-hydroxy acid family. Structurally related to gamma-hydroxybutyric acid (GHB), it has attracted interest in analytical chemistry and forensic toxicology due to its appearance as a novel psychoactive substance (NPS) and designer compound. Today, it is widely utilized as an analytical reference standard in forensic laboratories, medicinal chemistry, and pharmaceutical research.
Due to its well-characterized molecular structure and analytical relevance, GHV is frequently employed in drug metabolism studies, analytical method development, pharmaceutical research, and forensic identification.
GHV (4-Methyl GHB) is supplied strictly for laboratory, analytical, and scientific research purposes only. It is not approved for human or veterinary use.
What is GHV (4-Methyl GHB)?
GHV (γ-Hydroxyvaleric Acid) is a structural analog of GHB in which an additional methyl group is present on the carbon chain. It has been investigated in analytical and forensic settings because of its structural relationship to GHB and its metabolite pathways. GHV is also associated with γ-Valerolactone (GVL), which functions as its precursor in metabolic studies.
Research laboratories utilize GHV as a certified analytical reference material for forensic screening, metabolite identification, analytical method validation, and structure–activity relationship (SAR) research involving gamma-hydroxy acid analogs.
Chemische Struktur und Eigenschaften
GHV possesses several analytical characteristics valuable for laboratory research:
- Gamma-hydroxy acid core structure
- Structural analog of GHB
- Hohe analytische Stabilität
- Gut definiertes chromatographisches Verhalten
- Hervorragende Kompatibilität mit LC-MS/MS und GC-MS Instrumentierung
- Geeignet für analytische Referenz-Bibliothek-Entwicklung
- Zuverlässige forensic identification marker
These characteristics enable reproducible laboratory analyses and accurate analytical identification across modern forensic laboratories.
Wissenschaftliche Forschung Anwendungen
GHV is widely employed in:
- Analytische Chemie
- Medizinische Chemie
- Pharmakologische Forschung
- Droge Metabolismus-Untersuchungen
- Forensische Toxikologie
- Toxikologische screening
- Pharma-analytische Forschung
- Akademische Forschung
- Neuartige psychoaktive Substanzen (NPS) überwachung
- Referenz-standard-Entwicklung
Analytische Anwendungen
Professional laboratories commonly use GHV for:
- LC-MS/MS-Kalibrierung
- GC-MS Identifizierung
- LC-HRMS-Analyse
- HPLC-Methode Validierung
- Analytische Methode Entwicklung
- Forensische Drogen-screening
- Qualität assurance Prüfung
- Metabolite profiling
- Toxikologie-Referenz-Bibliothek-Erstellung
Its consistent analytical performance makes it a valuable reference material for forensic and pharmaceutical laboratories.
Pharmakologie-Forschung
Researchers investigate GHV in studies involving:
- Gamma-hydroxy acid analog characterization
- Droge Metabolismus und biotransformation
- Struktur-Aktivitäts-Beziehungs-(SAR-)Analyse
- Neuropharmacology
- Medizinische Chemie
- Analytische Toxikologie
- Forschung zu neuen psychoaktiven Substanzen
- Forensic pharmacology
These investigations contribute to advancements in analytical science and forensic toxicology.
Why Researchers Choose GHV
Researchers select GHV because it provides:
- Hohe analytische Reinheit
- Gut charakterisierten molekularen Struktur
- Stabile chromatographische Verhalten
- Ausgezeichnete massenspektrometrischen Antwort
- Erhebliche forensische Bedeutung
- Zuverlässige analytische Referenz Funktionen
- Breite Anwendbarkeit in der Toxikologie Labors
Verwandte Forschungs-Verbindungen
Researchers frequently compare GHV with related compounds including:
- GHB (Gamma-Hydroxybutyric Acid)
- GBL (Gamma-Butyrolactone)
- GVL (Gamma-Valerolactone)
- 1,4-Butanediol (1,4-BD)
- Aceburic Acid
- Valeric Acid
- Valerenic Acid
- Gamma-Hydroxy Acid Analogs
Vergleichende Studien unterstützen analytische Identifizierung, Stoffwechselforschung und Struktur-Aktivitäts-Beziehungsbeziehungen.
Lagerung und Handhabung
Für eine optimale Labor-Stabilität:
- Speichern Sie in luftdichten Labor-Container.
- Schützen Sie sich vor Hitze, Feuchtigkeit und direktem Sonnenlicht.
- Pflegen Speicher in einem kühlen, trockenen Umgebung.
- Griff mit geeigneten Labor persönliche Schutzausrüstung (PSA).
- Folgen institutionellen Labor-Sicherheits-Verfahren.
Häufig Gestellte Fragen
What is GHV (4-Methyl GHB)?
GHV is a synthetic gamma-hydroxy acid analog used as an analytical reference standard in forensic toxicology, medicinal chemistry, analytical chemistry, and pharmacology research.
Which laboratories use GHV?
Es wird allgemein verwendet, die von forensischen Labors, Toxikologie Labors, Pharma-Forscher, akademischen Institutionen und der analytischen Chemie Labors.
Die analytischen Techniken werden Häufig verwendet?
Researchers commonly analyze GHV using LC-MS/MS, GC-MS, LC-HRMS, HPLC, and related analytical techniques.
Why is GHV valuable in research?
Its well-characterized molecular profile, analytical stability, and forensic significance make it valuable for analytical method validation, metabolite identification, and reference standard development.
Is GHV intended only for research?
Yes. GHV is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.
Haftungsausschluss
GHV (4-Methyl GHB) is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary applications, therapeutic use, or diagnostic procedures. Users are responsible for complying with all applicable local laws, institutional policies, and laboratory safety regulations.





