What is Lexapro (Escitalopram)?
Lexapro (escitalopram) is one in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). It is taken by adults and adolescents at least 12 years of age to treat major depressive disorders. In adults, it is also used to treat anxiety.
How does Escitalopram work?
It affects the brain, altering certain chemical levels in people who may be suffering from depression or generalized anxiety disorder. On a chemical level, Lexapro is similar to Celexa (escitalopram) and both are SSRIs, along with Prozac (fluoxetine), Paxil (paroxetine) and (Zoloft) sertraline.
SSRIs affect neurotransmitters that communicate in the brain to send and receive information. Neurotransmitters are created by the nerves in the brain and are sent on to become attached to other nerves.
In some cases, the neurotransmitters do not attach to their intended receptors and end up returning to the nerves that created them. This imbalance of neurotransmitters is known as “reuptake” and experts believe this to be the cause of depression.
Lexapro stops serotonin from returning to its original nerve, resulting in higher levels of serotonin available in the brain to bind to receptors.
Escitalopram Dosing information
The amount you are prescribed will depend upon a variety of factors, including your age and medical condition. Generally, adults will begin with a daily dose of 10 mg. If necessary, this may be increased after a minimum of one week.
Typical dose for adults with generalized anxiety disorder:
Initially, 10 mg orally daily, increasing, if necessary, after a minimum of one week to 20 mg to be taken once each day.
Maintenance dose: 10 mg to 20 mg to be taken orally once each day
Maximum dose: 20 mg orally to be taken once each day
Please note:
- Treatment should be re-evaluated regularly to assess its efficiency. There have not been systematic studies of Lexapro’s efficacy beyond 8 weeks.
Typical dose for adults with major depressive disorder
Initially, 10 mg is to be taken orally once each day, to be increased after a minimum of one week, if necessary, to 20 mg once each day
Maintenance dose: 10 mg to 20 mg to be taken orally once each day
Maximum dose: 20 mg orally to be taken once each day
Please note:
- Several months of sustained pharmacological therapy, or even longer, may be needed to address acute episodes.
- Treatment should be regularly re-evaluated to assess the necessity for maintenance treatment.
Typical geriatric dose for major depressive disorder
The recommended dose is 10 mg to be taken orally once each day.
Typical pediatric dose for major depressive disorder
For adolescents aged 12 and older, the initial dose is 10 mg to be taken orally once each day. This may be increased after a minimum of 3 weeks of treatment, if necessary, to 20 mg to be taken once each day
Maintenance dose: 10 mg to 20 mg to be taken orally once each day
Maximum dose: 20 mg orally to be taken once each day
Please note:
- Sustained pharmacological therapy may need to continue for several months or longer beyond the initial response to an acute episode.
- The treatment should be re-evaluated regularly to assess the need for maintenance treatment.
How should you take Lexapro (Escitalopram)?
Lexapro should be used precisely as instructed on the label, or as your doctor has prescribed. Do not increase or decrease the amounts or use Lexapro for longer than has been recommended to you. Be sure to read all the information and instructions and follow the advice on the prescription label.
Try to take Lexapro at the same time each day. It can be taken with or without food.
Use a dosing syringe or a medicine dosing device to measure out a liquid dose, but do not use a normal kitchen spoon.
Make your doctor aware of any changes in your sexual activities after commencing your Lexapro treatment. Changes such as loss of sex drive and finding it difficult to achieve orgasm should be reported to your doctor. For men, trouble achieving an erection and ejaculation issues should also be reported to their doctor. Some sexual issues can be addressed with treatment.
Your treatment should be regularly re-evaluated so progress can be assessed. Children taking it should have their height and weight gain evaluated.
You mustn’t suddenly cease taking Escitalopram. If you do, you might experience unpleasant withdrawal symptoms. Instead, take your doctor’s advice and gradually taper your dose.
How to store Escitalopram
Be sure to store it away from moisture and heat, at room temperature.
Side Effects
Patients generally tolerate SSRIs, such as Escitalopram, well, compared to other kinds of antidepressants. Generally, a higher dosage of it will make it more likely that a patient will have more side effects. Gastrointestinal side effects, such as diarrhoea, are more likely with a high dosage of Lex apro.
Common side effects
Side effects appear to be the same for men and women, but they are slightly different between adults and children.
Amongst adults, the side effects may include:
- nausea
- sleepiness
- weakness
- dizziness
- anxiety
- sleeping trouble
- sexual problems, such as decreased sex drive and erectile dysfunction
- sweating
- shaking
- loss of appetitive
- dry mouth
- constipation
- infection
- yawning
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