{"id":34409,"date":"2026-09-28T21:11:24","date_gmt":"2026-09-28T21:11:24","guid":{"rendered":"https:\/\/izchem.com\/?post_type=product&p=34409"},"modified":"2026-09-28T21:11:31","modified_gmt":"2026-09-28T21:11:31","slug":"crl-40941","status":"publish","type":"product","link":"https:\/\/izchem.com\/es\/crl-40941\/","title":{"rendered":"CRL-40,941"},"content":{"rendered":"

CRL-40,941<\/strong>, com\u00fanmente conocido como Fladrafinil<\/strong> o Bisfluoroadrafinil<\/strong>es una de alta pureza eugeroic (wakefulness-promoting) research chemical<\/strong> belonging to the diphenylmethyl sulfinyl acetamide family. Developed by Laboratoire Lafon during investigations into next-generation wakefulness-promoting compounds, Fladrafinil is a fluorinated analogue of Adrafinil<\/strong> and is closely related to Modafinil<\/strong> and Flmodafinil (CRL-40,940)<\/strong>.<\/p>\n

Although never approved as a pharmaceutical medication, CRL-40,941 has become an important analytical reference material for laboratories studying wakefulness-promoting agents, dopamine transporter pharmacology, medicinal chemistry, metabolism, and neuropharmacology.<\/p>\n

What is CRL-40,941 (Fladrafinil)?<\/h1>\n

Fladrafinil is a fluorinated derivative of Adrafinil developed during research into compounds that promote wakefulness and cognitive function. Structurally, it differs from Adrafinil by the addition of fluorine atoms on both aromatic rings, a modification used in medicinal chemistry to investigate how halogen substitution affects pharmacological properties, metabolic stability, and receptor interactions.<\/p>\n

Because of its defined chemical profile, CRL-40,941 is widely used as a reference standard in analytical laboratories and pharmaceutical research.<\/p>\n

Estructura y Propiedades qu\u00edmicas<\/h1>\n

CRL-40,941 contains several notable structural features:<\/p>\n

    \n
  • Diphenylmethyl sulfoxide core<\/li>\n
  • Hydroxamic acid functionality<\/li>\n
  • Two para-fluorophenyl rings<\/li>\n
  • Sulfinyl linkage<\/li>\n
  • Alta estabilidad qu\u00edmica<\/li>\n
  • Polvo cristalino de grado de laboratorio<\/li>\n<\/ul>\n

    These characteristics make it useful for chromatographic analysis, analytical validation, and medicinal chemistry investigations.<\/p>\n

    La Investigaci\u00f3n Farmacol\u00f3gica<\/h1>\n

    Scientific literature indicates that Fladrafinil belongs to the same pharmacological family as Modafinil and Adrafinil. Research suggests that compounds within this family influence dopamine transporter (DAT)<\/strong> activity, making them valuable tools for studying wakefulness mechanisms and central nervous system pharmacology.<\/p>\n

    Current research areas include:<\/p>\n

      \n
    • Dopamine transporter (DAT) investigations<\/li>\n
    • Wakefulness-promoting compound research<\/li>\n
    • Neurochemical signaling<\/li>\n
    • Cognitive enhancer pharmacology<\/li>\n
    • Comparative studies with Modafinil analogues<\/li>\n
    • Relaci\u00f3n estructura\u2013actividad (SAR), el an\u00e1lisis<\/li>\n
    • Drug metabolism and pharmacokinetics<\/li>\n<\/ul>\n

      Animal studies have also explored behavioral effects, including wakefulness and anti-aggressive activity, although further research is needed to fully characterize its pharmacological profile.<\/p>\n

      Las Aplicaciones De La Investigaci\u00f3n Cient\u00edfica<\/h1>\n

      CRL-40,941 is frequently used in:<\/p>\n

        \n
      • Desarrollo farmac\u00e9utico<\/li>\n
      • Laboratorios de qu\u00edmica medicinal<\/li>\n
      • Investigaci\u00f3n en neurofarmacolog\u00eda<\/li>\n
      • Acad\u00e9mico de la neurociencia<\/li>\n
      • qu\u00edmica anal\u00edtica<\/li>\n
      • Metabolismo de los f\u00e1rmacos investigaciones<\/li>\n
      • Toxicolog\u00eda forense<\/li>\n
      • Est\u00e1ndar de referencia de la producci\u00f3n<\/li>\n
      • Laboratorios de control de calidad<\/li>\n<\/ul>\n

        Aplicaciones Anal\u00edticas<\/h1>\n

        Researchers utilize Fladrafinil for:<\/p>\n

          \n
        • LC-MS\/MS method development<\/li>\n
        • GC-MS analytical calibration<\/li>\n
        • HPLC analysis<\/li>\n
        • Espectrometr\u00eda de masas de alta resoluci\u00f3n (HRMS)<\/li>\n
        • Creaci\u00f3n de bibliotecas de referencia<\/li>\n
        • La validaci\u00f3n del m\u00e9todo<\/li>\n
        • Identificaci\u00f3n compuesta<\/li>\n
        • Stability testing<\/li>\n
        • Quality assurance protocols<\/li>\n<\/ul>\n

          Its well-defined analytical profile supports accurate differentiation from related compounds such as Modafinil, Adrafinil, and Flmodafinil.<\/p>\n

          Why Researchers Choose CRL-40,941<\/h1>\n

          Researchers value Fladrafinil because it offers:<\/p>\n

            \n
          • Bien caracterizada la estructura molecular<\/li>\n
          • De alta pureza anal\u00edtica<\/li>\n
          • Comportamiento cromatogr\u00e1fico fiable<\/li>\n
          • Excelente reproducibilidad anal\u00edtica<\/li>\n
          • Useful SAR comparison with Modafinil analogues<\/li>\n
          • Broad application in neuropharmacology<\/li>\n
          • Rendimiento de laboratorio constante<\/li>\n<\/ul>\n

            La Investigaci\u00f3n Relacionada Con Los Compuestos<\/h1>\n

            Fladrafinil is commonly studied alongside:<\/p>\n

              \n
            • Modafinil<\/li>\n
            • Armodafinil<\/li>\n
            • Adrafinil<\/li>\n
            • Flmodafinil (CRL-40,940)<\/li>\n
            • CE-123<\/li>\n
            • Modafinil analogues<\/li>\n
            • Eugeroic research compounds<\/li>\n<\/ul>\n

              Comparative investigations help researchers understand transporter interactions, metabolism, and structural modifications within the eugeroic class.<\/p>\n

              El almacenamiento y la Manipulaci\u00f3n<\/h1>\n

              Para una \u00f3ptima laboratorio de estabilidad:<\/p>\n

                \n
              • Tienda en herm\u00e9ticos recipientes de laboratorio.<\/li>\n
              • Proteger de la humedad.<\/li>\n
              • Keep away from direct sunlight.<\/li>\n
              • Mantener recomendados laboratorio de temperaturas de almacenamiento.<\/li>\n
              • Manipular utilizando el equipo de protecci\u00f3n individual (EPI) de laboratorio adecuado.<\/li>\n
              • Siga institucional de laboratorio, procedimientos de seguridad.<\/li>\n<\/ul>\n

                Preguntas frecuentes<\/h1>\n

                What is CRL-40,941?<\/h3>\n

                CRL-40,941 (Fladrafinil) is a fluorinated analogue of Adrafinil used as an analytical reference standard in neuropharmacology, medicinal chemistry, pharmaceutical research, and forensic toxicology.<\/p>\n

                Which laboratories use Fladrafinil?<\/h3>\n

                It is commonly used by pharmaceutical companies, forensic laboratories, academic institutions, medicinal chemists, and analytical chemistry laboratories.<\/p>\n

                Which analytical techniques are suitable for CRL-40,941?<\/h3>\n

                Researchers commonly analyze Fladrafinil using LC-MS\/MS, GC-MS, HPLC, and HRMS for calibration, compound identification, and analytical method validation.<\/p>\n

                Why is Fladrafinil valuable for research?<\/h3>\n

                Its defined molecular structure, relationship to Modafinil analogues, and analytical consistency make it useful for pharmacological research, transporter studies, and medicinal chemistry investigations.<\/p>\n

                Is CRL-40,941 intended only for research?<\/h3>\n

                S\u00ed. Este producto se suministra exclusivamente para laboratorio, anal\u00edticos, cient\u00edficos, educativos y de los prop\u00f3sitos de la investigaci\u00f3n.<\/p>\n

                Descargo de responsabilidad<\/h1>\n

                CRL-40,941 (Fladrafinil)<\/strong> se suministra Estrictamente para fines de investigaci\u00f3n de laboratorio, anal\u00edtica, cient\u00edfica y educativa \u00fanicamente.<\/strong>. Es not intended for human consumption, therapeutic use, veterinary applications, medical treatment, or diagnostic purposes<\/strong>. Researchers are responsible for complying with all applicable laws, institutional policies, and laboratory safety regulations.<\/p>","protected":false},"excerpt":{"rendered":"

                  \n
                • Nombre De Producto:<\/strong>CRL-40,941<\/li>\n
                • Nombres Alternativos: <\/strong>Fladrafinil, Fluorafinil, Bisfluoroadrafinil<\/li>\n
                • Clase Qu\u00edmica: <\/strong>Diphenylmethyl Sulfinyl Acetamide<\/li>\n
                • Categor\u00eda de investigaci\u00f3n: <\/strong>Est\u00e1ndar De Referencia Anal\u00edtica<\/li>\n<\/ul>","protected":false},"featured_media":34429,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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