Spravato (Esketamine Nasal Spray)

Spravato (Esketamine Nasal Spray)

How Esketamine Works

Spravato is a medication used for the treatment of treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal ideation in adults. It contains ketamine, which is a form of ketamine, a dissociative anaesthetic.

The exact mechanism of how ketamine works to alleviate depression is not fully understood, but it is believed to involve the modulation of glutamate, an important neurotransmitter in the brain. By acting on the glutamate system, ketamine helps to restore synaptic connections and improve mood regulation in individuals with depression.

Side Effects of Spravato Esketamine

• Disassociation (feeling disconnected from oneself or reality)
• Dizziness
• Sedation
• Headache
• Nausea
• Increased blood pressure
• Vomiting
• Vertigo
• Blurred vision

These side effects are typically mild to moderate in severity and may diminish with repeated doses. However, some individuals may experience more serious adverse reactions, so monitoring for any unusual symptoms and consulting a healthcare professional is essential.

Indications

• Treatment-resistant depression (TRD) in adults
• Major depressive disorder (MDD) with suicidal ideation in adults

Contraindications

• Hypersensitivity to esketamine or any component of the formulation
• History of psychosis or psychotic disorder
• Uncontrolled hypertension
• Substance abuse or dependence, including alcohol
• Recent use of monoamine oxidase inhibitors (MAOIs)
• Best place to buy esketamine nasal spray
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