{"id":34326,"date":"2026-09-28T21:11:04","date_gmt":"2026-09-28T21:11:04","guid":{"rendered":"https:\/\/izchem.com\/?post_type=product&#038;p=34326"},"modified":"2026-09-28T21:11:13","modified_gmt":"2026-09-28T21:11:13","slug":"4-ho-det-2","status":"publish","type":"product","link":"https:\/\/izchem.com\/pt\/4-ho-det-2\/","title":{"rendered":"4-HO-DET"},"content":{"rendered":"<p>4-HO-DET (4-Hydroxy-N,N-Diethyltryptamine), also known as Ethocin, is a substituted tryptamine research compound belonging to the 4-hydroxytryptamine family. Structurally related to psilocin (4-HO-DMT), DET, and other psychedelic tryptamines, 4-HO-DET has been studied in analytical chemistry, receptor pharmacology, neurochemical research, and compound characterization investigations.<\/p>\n<p>Researchers investigate 4-HO-DET for its chemical structure, receptor binding profile, analytical properties, and structure-activity relationships among substituted tryptamines. The compound has historical significance in scientific literature dating back to the 1960s and remains relevant in modern analytical and pharmacological research.<\/p>\n<h2>What Is 4-HO-DET?<\/h2>\n<p>4-HO-DET is a 4-hydroxylated tryptamine derivative and the N,N-diethyl analogue of psilocin (4-HO-DMT). It belongs to the broader family of substituted tryptamines that are frequently referenced in receptor research, neurochemical investigations, and analytical chemistry.<\/p>\n<p>Researchers may study 4-HO-DET to better understand its receptor interactions, molecular properties, analytical behavior, and structural relationships with related tryptamine compounds.<\/p>\n<h2>Estrutura Qu\u00edmica e Classifica\u00e7\u00e3o<\/h2>\n<p>4-HO-DET belongs to the substituted tryptamine family and contains several defining structural features:<\/p>\n<ul>\n<li>Tryptamine molecular backbone<\/li>\n<li>Hydroxyl substitution at the 4-position<\/li>\n<li>N,N-Diethyl substitution<\/li>\n<li>Indole-based structure<\/li>\n<\/ul>\n<p>These characteristics place the compound among several well-known tryptamine analogues used in scientific research.<\/p>\n<h2>Liga\u00e7\u00e3o ao recetor e investiga\u00e7\u00e3o farmacol\u00f3gica<\/h2>\n<p>Published studies have reported that 4-HO-DET interacts with multiple serotonin receptor systems.<\/p>\n<p>Research has identified measurable affinity for:<\/p>\n<ul>\n<li>5-HT2A Receptors<\/li>\n<li>5-HT2B Receptors<\/li>\n<li>5-HT2C Receptors<\/li>\n<li>5-HT1A Receptors<\/li>\n<li>Additional serotonin receptor subtypes<\/li>\n<\/ul>\n<p>Scientific investigations suggest that 4-HO-DET functions as a non-selective serotonin receptor agonist and is commonly referenced in receptor pharmacology research.<\/p>\n<h2>Scientific Significance of 4-HO-DET Research<\/h2>\n<p>Scientific interest in 4-HO-DET stems from its relevance to:<\/p>\n<ul>\n<li>Tryptamine research<\/li>\n<li>Farmacologia dos receptores<\/li>\n<li>Investiga\u00e7\u00f5es neuroqu\u00edmicas<\/li>\n<li>Qu\u00edmica anal\u00edtica<\/li>\n<li>Estudos de relacionamento estrutura-atividade<\/li>\n<li>Caracteriza\u00e7\u00e3o do composto<\/li>\n<\/ul>\n<p>Research involving 4-HO-DET contributes to scientific understanding of serotonin receptor interactions and substituted tryptamine chemistry.<\/p>\n<h2>Why Researchers Study 4-HO-DET<\/h2>\n<p>Researchers may reference 4-HO-DET in studies involving:<\/p>\n<ul>\n<li>Serotonin receptor research<\/li>\n<li>Investiga\u00e7\u00f5es neuroqu\u00edmicas<\/li>\n<li>Qu\u00edmica anal\u00edtica<\/li>\n<li>Tryptamine characterization<\/li>\n<li>Receptor binding analysis<\/li>\n<li>Testes de laborat\u00f3rio<\/li>\n<li>Documenta\u00e7\u00e3o cient\u00edfica<\/li>\n<li>Comparative pharmacological research<\/li>\n<\/ul>\n<p>These investigations contribute to improved understanding of receptor activity and molecular structure relationships.<\/p>\n<h2>Analytical Characterization of 4-HO-DET<\/h2>\n<p>Analytical laboratories may use multiple techniques to identify and characterize 4-HO-DET.<\/p>\n<p>Os m\u00e9todos anal\u00edticos comuns incluem:<\/p>\n<ul>\n<li>Cromatografia L\u00edquida de Alto Desempenho (HPLC)<\/li>\n<li>Cromatografia L\u00edquida-Espectrometria de Massa (LC-MS)<\/li>\n<li>Cromatografia Gasosa-Espectrometria de Massa (GC-MS)<\/li>\n<li>An\u00e1lise Espectrosc\u00f3pica<\/li>\n<li>Receptor Binding Assays<\/li>\n<li>Procedimentos de verifica\u00e7\u00e3o de compostos<\/li>\n<\/ul>\n<p>These methods help generate reliable analytical data for scientific investigations.<\/p>\n<h2>Compostos e An\u00e1logos Relacionados<\/h2>\n<p>Researchers studying 4-HO-DET may also encounter:<\/p>\n<ul>\n<li>Psilocina (4-HO-DMT)<\/li>\n<li>Diethyltryptamine (DET)<\/li>\n<li>4-HO-MET<\/li>\n<li>4-HO-DPT<\/li>\n<li>4-HO-EPT<\/li>\n<li>5-MeO-DET<\/li>\n<li>4-AcO-DET<\/li>\n<li>Ethocybin (4-PO-DET)<\/li>\n<\/ul>\n<p>These compounds are frequently referenced in comparative tryptamine research and structure-activity investigations.<\/p>\n<h2>Historical Research Background<\/h2>\n<p>4-HO-DET was first described in scientific literature during the early 1960s and was developed by researchers at Sandoz. The compound later appeared in scientific investigations involving tryptamine chemistry and receptor pharmacology.<\/p>\n<p>Its documented history makes it a notable compound within the broader field of substituted tryptamine research.<\/p>\n<h2>Research Applications of 4-HO-DET<\/h2>\n<p>As aplica\u00e7\u00f5es cient\u00edficas potenciais incluem:<\/p>\n<ul>\n<li>Estudos de liga\u00e7\u00e3o ao recetor<\/li>\n<li>Investiga\u00e7\u00f5es neuroqu\u00edmicas<\/li>\n<li>Verifica\u00e7\u00e3o anal\u00edtica<\/li>\n<li>Caracteriza\u00e7\u00e3o estrutural<\/li>\n<li>Comparative tryptamine research<\/li>\n<li>Desenvolvimento de m\u00e9todos laboratoriais<\/li>\n<li>Avalia\u00e7\u00e3o do padr\u00e3o de refer\u00eancia<\/li>\n<li>Documenta\u00e7\u00e3o cient\u00edfica<\/li>\n<\/ul>\n<h2>Armazenamento e manuseio em laborat\u00f3rio<\/h2>\n<p>Research compounds should be stored under appropriate laboratory conditions to preserve analytical integrity and maintain sample stability. Proper storage helps ensure reliable research outcomes and consistent analytical performance.<\/p>\n<p>All handling and research activities should be conducted by qualified professionals following laboratory safety standards and applicable regulations.<\/p>\n<h2>Perguntas frequentes<\/h2>\n<h3>What is 4-HO-DET?<\/h3>\n<p>4-HO-DET (4-Hydroxy-N,N-Diethyltryptamine) is a substituted tryptamine research compound commonly referenced in analytical chemistry, receptor pharmacology, and neurochemical investigations.<\/p>\n<h3>What is the molecular formula of 4-HO-DET?<\/h3>\n<p>A f\u00f3rmula molecular de 4-HO-DET \u00e9 <strong>C14H20N2O<\/strong>.<\/p>\n<h3>Qual \u00e9 o peso molecular de 4-HO-DET?<\/h3>\n<p>The molecular weight of 4-HO-DET is <strong>232.327 g\/mol<\/strong>.<\/p>\n<h3>What chemical family does 4-HO-DET belong to?<\/h3>\n<p>4-HO-DET belongs to the substituted tryptamine and 4-hydroxytryptamine families.<\/p>\n<h3>Which receptors are commonly studied with 4-HO-DET?<\/h3>\n<p>Research commonly focuses on serotonin receptor systems including 5-HT2A, 5-HT2B, 5-HT2C, and 5-HT1A receptors.<\/p>\n<h3>What compounds are structurally related to 4-HO-DET?<\/h3>\n<p>Related compounds include psilocin (4-HO-DMT), DET, 4-HO-MET, 4-HO-DPT, 4-HO-EPT, and 4-AcO-DET.<\/p>\n<h3>What analytical methods are used to study 4-HO-DET?<\/h3>\n<p>Researchers commonly use HPLC, LC-MS, GC-MS, spectroscopy, receptor binding assays, and compound verification techniques.<\/p>\n<h3>Why is 4-HO-DET important in scientific research?<\/h3>\n<p>It is referenced because of its relevance to receptor pharmacology, tryptamine chemistry, neurochemical investigations, and structure-activity relationship research.<\/p>\n<h2>Isen\u00e7\u00e3o de responsabilidade educacional e de pesquisa<\/h2>\n<p>Este produto destina-se estritamente a fins cient\u00edficos, educacionais e de pesquisa laboratorial. N\u00e3o se destina ao consumo humano, uso m\u00e9dico, uso veterin\u00e1rio ou aplica\u00e7\u00f5es terap\u00eauticas. Todo manuseio e pesquisa devem ser realizados por profissionais qualificados de acordo com as leis, regulamentos e padr\u00f5es de seguran\u00e7a laboratoriais aplic\u00e1veis.<\/p>","protected":false},"excerpt":{"rendered":"<ul>\n<li class=\"isSelectedEnd\"><strong>Nome do composto: <\/strong>4-Hydroxy-N,N-Diethyltryptamine<\/li>\n<li class=\"isSelectedEnd\"><strong>Nomes Alternativos: <\/strong>4-HO-DET,4-OH-DET,Ethocin,CZ-74,CZ74<\/li>\n<li class=\"isSelectedEnd\"><strong>N\u00famero CAS: <\/strong>22204-89-3<\/li>\n<li class=\"isSelectedEnd\"><strong>Tipo: <\/strong>Pesquisa Qu\u00edmica<\/li>\n<li class=\"isSelectedEnd\"><strong>Fam\u00edlia Qu\u00edmica: <\/strong>Triptamina Substitu\u00edda<\/li>\n<li><strong>Categoria de pesquisa: <\/strong>Composto de Pesquisa Anal\u00edtica<\/li>\n<\/ul>","protected":false},"featured_media":34355,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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Name: 4-Hydroxy-N,N-Diethyltryptamine Alternative Names: 4-HO-DET,4-OH-DET,Ethocin,CZ-74,CZ74 CAS Number: 22204-89-3 Type: Research Chemical Chemical Family: Substituted Tryptamine Research Category: Analytical Research Compound","_links":{"self":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product\/34326","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/comments?post=34326"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/media\/34355"}],"wp:attachment":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/media?parent=34326"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_brand?post=34326"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_cat?post=34326"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_tag?post=34326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}