{"id":34374,"date":"2026-09-28T21:11:15","date_gmt":"2026-09-28T21:11:15","guid":{"rendered":"https:\/\/izchem.com\/?post_type=product&#038;p=34374"},"modified":"2026-09-28T21:11:22","modified_gmt":"2026-09-28T21:11:22","slug":"rti-111-dichloropane","status":"publish","type":"product","link":"https:\/\/izchem.com\/pt\/rti-111-dichloropane\/","title":{"rendered":"RTI-111 (Dichloropane)"},"content":{"rendered":"<p data-start=\"26\" data-end=\"465\">RTI-111, also known as Dichloropane, is a synthetic phenyltropane research compound originally developed for investigations into monoamine transporter pharmacology. Due to its well-characterized molecular structure and activity at dopamine, norepinephrine, and serotonin transporters, RTI-111 has become an important analytical reference standard in medicinal chemistry, neuropharmacology, forensic toxicology, and analytical laboratories.<\/p>\n<p data-start=\"467\" data-end=\"724\">Its unique structural characteristics and relevance in neurotransmitter transporter research make RTI-111 valuable for analytical method development, structure\u2013activity relationship (SAR) studies, drug metabolism investigations, and pharmaceutical research.<\/p>\n<p data-start=\"726\" data-end=\"869\">RTI-111 is supplied strictly for laboratory, analytical, and scientific research purposes only. It is not approved for human or veterinary use.<\/p>\n<h1 data-section-id=\"3z0knt\" data-start=\"876\" data-end=\"909\">What is RTI-111 (Dichloropane)?<\/h1>\n<p data-start=\"911\" data-end=\"1190\">RTI-111 is a synthetic phenyltropane derivative belonging to the monoamine transporter inhibitor class. It is structurally related to cocaine analogs but was developed primarily as a research compound for studying dopamine, norepinephrine, and serotonin transporter interactions.<\/p>\n<p data-start=\"1192\" data-end=\"1442\">Research laboratories utilize RTI-111 as a certified analytical reference material to support transporter research, analytical method validation, forensic screening, metabolite identification, and structure\u2013activity relationship (SAR) investigations.<\/p>\n<h1 data-section-id=\"ccn919\" data-start=\"1449\" data-end=\"1484\">Estrutura qu\u00edmica e Propriedades<\/h1>\n<p data-start=\"1486\" data-end=\"1572\">RTI-111 possesses several analytical characteristics valuable for laboratory research:<\/p>\n<ul data-start=\"1574\" data-end=\"1885\">\n<li data-section-id=\"qy15wz\" data-start=\"1574\" data-end=\"1604\">Phenyltropane core structure<\/li>\n<li data-section-id=\"1ig297a\" data-start=\"1605\" data-end=\"1653\">Dichlorophenyl substituted molecular framework<\/li>\n<li data-section-id=\"1x6h50r\" data-start=\"1654\" data-end=\"1681\">Elevada estabilidade anal\u00edtica<\/li>\n<li data-section-id=\"13hojod\" data-start=\"1682\" data-end=\"1721\">Comportamento cromatogr\u00e1fico bem definido<\/li>\n<li data-section-id=\"1my176h\" data-start=\"1722\" data-end=\"1787\">Excelente compatibilidade com instrumentos LC-MS\/MS e GC-MS.<\/li>\n<li data-section-id=\"cwl8ml\" data-start=\"1788\" data-end=\"1843\">Adequado para o desenvolvimento de bibliotecas de refer\u00eancia anal\u00edticas.<\/li>\n<li data-section-id=\"1xhgg4x\" data-start=\"1844\" data-end=\"1885\">Marcador de identifica\u00e7\u00e3o forense fi\u00e1vel<\/li>\n<\/ul>\n<p data-start=\"1887\" data-end=\"1995\">Estas caracter\u00edsticas permitem an\u00e1lises laboratoriais reproduz\u00edveis e identifica\u00e7\u00e3o anal\u00edtica de elevada fiabilidade.<\/p>\n<h1 data-section-id=\"15qglsl\" data-start=\"2002\" data-end=\"2036\">A Investiga\u00e7\u00e3o Cient\u00edfica Aplica\u00e7\u00f5es<\/h1>\n<p data-start=\"2038\" data-end=\"2068\">RTI-111 is widely employed in:<\/p>\n<ul data-start=\"2070\" data-end=\"2362\">\n<li data-section-id=\"1h4ibl2\" data-start=\"2070\" data-end=\"2092\">Qu\u00edmica anal\u00edtica<\/li>\n<li data-section-id=\"10pasf6\" data-start=\"2093\" data-end=\"2114\">Qu\u00edmica Medicinal<\/li>\n<li data-section-id=\"xlv0dg\" data-start=\"2115\" data-end=\"2143\">Investiga\u00e7\u00e3o em neurofarmacologia<\/li>\n<li data-section-id=\"52efec\" data-start=\"2144\" data-end=\"2176\">Investiga\u00e7\u00f5es sobre o metabolismo dos f\u00e1rmacos<\/li>\n<li data-section-id=\"xny62i\" data-start=\"2177\" data-end=\"2198\">Toxicologia forense<\/li>\n<li data-section-id=\"10c9uxt\" data-start=\"2199\" data-end=\"2224\">Triagem toxicol\u00f3gica<\/li>\n<li data-section-id=\"bgx9ge\" data-start=\"2225\" data-end=\"2261\">Investiga\u00e7\u00e3o anal\u00edtica farmac\u00eautica<\/li>\n<li data-section-id=\"izno38\" data-start=\"2262\" data-end=\"2281\">Pesquisa acad\u00eamica<\/li>\n<li data-section-id=\"1mxs3wo\" data-start=\"2282\" data-end=\"2314\">investiga\u00e7\u00e3o sobre transportadores de monoaminas<\/li>\n<li data-section-id=\"olmrrj\" data-start=\"2315\" data-end=\"2362\">Estudos estrutura-atividade (SAR)<\/li>\n<\/ul>\n<h1 data-section-id=\"1r8f9bb\" data-start=\"2369\" data-end=\"2394\">Aplica\u00e7\u00f5es Anal\u00edticas<\/h1>\n<p data-start=\"2396\" data-end=\"2447\">Professional laboratories commonly use RTI-111 for:<\/p>\n<ul data-start=\"2449\" data-end=\"2687\">\n<li data-section-id=\"1hrzeen\" data-start=\"2449\" data-end=\"2471\">LC-MS\/MS de calibra\u00e7\u00e3o<\/li>\n<li data-section-id=\"zjj6c5\" data-start=\"2472\" data-end=\"2494\">Identifica\u00e7\u00e3o por GC-MS<\/li>\n<li data-section-id=\"1s1ni0s\" data-start=\"2495\" data-end=\"2513\">An\u00e1lise LC-HRMS<\/li>\n<li data-section-id=\"yao7l7\" data-start=\"2514\" data-end=\"2538\">Valida\u00e7\u00e3o do m\u00e9todo HPLC<\/li>\n<li data-section-id=\"169jlqk\" data-start=\"2539\" data-end=\"2570\">Desenvolvimento de m\u00e9todos anal\u00edticos<\/li>\n<li data-section-id=\"wzbuq1\" data-start=\"2571\" data-end=\"2596\">rastreio forense de drogas<\/li>\n<li data-section-id=\"1w8xwfw\" data-start=\"2597\" data-end=\"2624\">Teste de controle de qualidade<\/li>\n<li data-section-id=\"n056le\" data-start=\"2625\" data-end=\"2647\">Perfil metab\u00f3lico<\/li>\n<li data-section-id=\"314bm6\" data-start=\"2648\" data-end=\"2687\">Cria\u00e7\u00e3o de biblioteca de refer\u00eancia em toxicologia<\/li>\n<\/ul>\n<p data-start=\"2689\" data-end=\"2797\">O seu desempenho anal\u00edtico consistente torna-o valioso para os laborat\u00f3rios forenses e farmac\u00eauticos modernos.<\/p>\n<h1 data-section-id=\"1219ovd\" data-start=\"2804\" data-end=\"2827\">Investiga\u00e7\u00e3o em Farmacologia<\/h1>\n<p data-start=\"2829\" data-end=\"2882\">Researchers investigate RTI-111 in studies involving:<\/p>\n<ul data-start=\"2884\" data-end=\"3181\">\n<li data-section-id=\"snjb7k\" data-start=\"2884\" data-end=\"2921\">Pesquisa do transportador de dopamina (DAT)<\/li>\n<li data-section-id=\"1nyh907\" data-start=\"2922\" data-end=\"2965\">Investiga\u00e7\u00e3o sobre o transportador de norepinefrina (NET)<\/li>\n<li data-section-id=\"8h8mjx\" data-start=\"2966\" data-end=\"3005\">Serotonin transporter (SERT) research<\/li>\n<li data-section-id=\"77vh46\" data-start=\"3006\" data-end=\"3046\">Monoamine transporter characterization<\/li>\n<li data-section-id=\"mtgt90\" data-start=\"3047\" data-end=\"3095\">Rela\u00e7\u00e3o estrutura\u2013atividade (SAR) de an\u00e1lise<\/li>\n<li data-section-id=\"178dee1\" data-start=\"3096\" data-end=\"3135\">Metabolismo e biotransforma\u00e7\u00e3o de f\u00e1rmacos<\/li>\n<li data-section-id=\"10pasf6\" data-start=\"3136\" data-end=\"3157\">Qu\u00edmica Medicinal<\/li>\n<li data-section-id=\"yoprtn\" data-start=\"3158\" data-end=\"3181\">Toxicologia anal\u00edtica<\/li>\n<\/ul>\n<p data-start=\"3183\" data-end=\"3281\">Estas investiga\u00e7\u00f5es contribuem para os avan\u00e7os na ci\u00eancia anal\u00edtica e na investiga\u00e7\u00e3o farmac\u00eautica.<\/p>\n<h1 data-section-id=\"dopcvn\" data-start=\"3288\" data-end=\"3320\">Why Researchers Choose RTI-111<\/h1>\n<p data-start=\"3322\" data-end=\"3369\">Researchers select RTI-111 because it provides:<\/p>\n<ul data-start=\"3371\" data-end=\"3666\">\n<li data-section-id=\"4ws8wt\" data-start=\"3371\" data-end=\"3395\">De alta pureza anal\u00edtica<\/li>\n<li data-section-id=\"12r202z\" data-start=\"3396\" data-end=\"3436\">Bem-caracteriza-se a estrutura molecular<\/li>\n<li data-section-id=\"172x1se\" data-start=\"3437\" data-end=\"3470\">Comportamento cromatogr\u00e1fico est\u00e1vel<\/li>\n<li data-section-id=\"14ul5xn\" data-start=\"3471\" data-end=\"3510\">Excelente resposta em espectrometria de massas<\/li>\n<li data-section-id=\"1g83u67\" data-start=\"3511\" data-end=\"3555\">Significant pharmacological research value<\/li>\n<li data-section-id=\"lnoued\" data-start=\"3556\" data-end=\"3600\">Capacidades de refer\u00eancia anal\u00edtica fi\u00e1veis<\/li>\n<li data-section-id=\"313g7m\" data-start=\"3601\" data-end=\"3666\">Broad applicability in neuroscience and toxicology laboratories<\/li>\n<\/ul>\n<h1 data-section-id=\"14cbx0i\" data-start=\"3673\" data-end=\"3701\">A Investiga\u00e7\u00e3o Relacionada Com Compostos<\/h1>\n<p data-start=\"3703\" data-end=\"3775\">Researchers frequently compare RTI-111 with related compounds including:<\/p>\n<ul data-start=\"3777\" data-end=\"3895\">\n<li data-section-id=\"5wumjo\" data-start=\"3777\" data-end=\"3786\">Coca\u00edna<\/li>\n<li data-section-id=\"vhfdo9\" data-start=\"3787\" data-end=\"3800\">Tesofensine<\/li>\n<li data-section-id=\"8lxb6h\" data-start=\"3801\" data-end=\"3815\">Brasofensine<\/li>\n<li data-section-id=\"1ah64d1\" data-start=\"3816\" data-end=\"3825\">NS-2359<\/li>\n<li data-section-id=\"siltg\" data-start=\"3826\" data-end=\"3836\">3,4-DCMP<\/li>\n<li data-section-id=\"1tqhole\" data-start=\"3837\" data-end=\"3845\">O-2390<\/li>\n<li data-section-id=\"7dp6ko\" data-start=\"3846\" data-end=\"3854\">RTI-31<\/li>\n<li data-section-id=\"7dp6q2\" data-start=\"3855\" data-end=\"3863\">RTI-55<\/li>\n<li data-section-id=\"17wpjf0\" data-start=\"3864\" data-end=\"3876\">WIN 35,428<\/li>\n<li data-section-id=\"12zuqme\" data-start=\"3877\" data-end=\"3895\">Methylecgonidine<\/li>\n<\/ul>\n<p data-start=\"3897\" data-end=\"4045\">Comparative studies support analytical identification, transporter research, metabolism studies, and structure\u2013activity relationship investigations.<\/p>\n<h1 data-section-id=\"1qeuwpn\" data-start=\"4052\" data-end=\"4074\">Armazenamento e Manipula\u00e7\u00e3o<\/h1>\n<p data-start=\"4076\" data-end=\"4109\">Para um \u00f3ptimo laborat\u00f3rio de estabilidade:<\/p>\n<ul data-start=\"4111\" data-end=\"4380\">\n<li data-section-id=\"16yoxud\" data-start=\"4111\" data-end=\"4153\">Loja em herm\u00e9tico recipientes de laborat\u00f3rio.<\/li>\n<li data-section-id=\"y5bdwd\" data-start=\"4154\" data-end=\"4205\">Proteger do calor, da humidade e da luz solar direta.<\/li>\n<li data-section-id=\"folo7t\" data-start=\"4206\" data-end=\"4252\">Conservar em local fresco e seco.<\/li>\n<li data-section-id=\"esma3t\" data-start=\"4253\" data-end=\"4327\">Manuseie utilizando os equipamentos de prote\u00e7\u00e3o individual (EPI) de laborat\u00f3rio adequados.<\/li>\n<li data-section-id=\"18543zj\" data-start=\"4328\" data-end=\"4380\">Siga institucionais laborat\u00f3rio de procedimentos de seguran\u00e7a.<\/li>\n<\/ul>\n<h1 data-section-id=\"hkd5a4\" data-start=\"4387\" data-end=\"4415\">Perguntas frequentes<\/h1>\n<h3 data-section-id=\"1ka187u\" data-start=\"4417\" data-end=\"4437\">What is RTI-111?<\/h3>\n<p data-start=\"4439\" data-end=\"4639\">RTI-111 (Dichloropane) is a synthetic phenyltropane research compound used as an analytical reference standard in neuropharmacology, forensic toxicology, medicinal chemistry, and analytical chemistry.<\/p>\n<h3 data-section-id=\"12u5woh\" data-start=\"4641\" data-end=\"4676\">Which laboratories use RTI-111?<\/h3>\n<p data-start=\"4678\" data-end=\"4864\">It is commonly used by forensic laboratories, toxicology laboratories, neuroscience researchers, pharmaceutical researchers, academic institutions, and analytical chemistry laboratories.<\/p>\n<h3 data-section-id=\"1pbkqbu\" data-start=\"4866\" data-end=\"4916\">Que t\u00e9cnicas anal\u00edticas s\u00e3o comummente utilizadas?<\/h3>\n<p data-start=\"4918\" data-end=\"5027\">Researchers commonly analyze RTI-111 using LC-MS\/MS, GC-MS, LC-HRMS, HPLC, and related analytical techniques.<\/p>\n<h3 data-section-id=\"1al0f1o\" data-start=\"5029\" data-end=\"5069\">Why is RTI-111 valuable in research?<\/h3>\n<p data-start=\"5071\" data-end=\"5318\">Its well-characterized molecular profile, transporter research significance, analytical stability, and forensic relevance make it valuable for method validation, metabolite identification, transporter studies, and analytical reference development.<\/p>\n<h3 data-section-id=\"108lwnv\" data-start=\"5320\" data-end=\"5362\">Is RTI-111 intended only for research?<\/h3>\n<p data-start=\"5364\" data-end=\"5475\">Yes. RTI-111 is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.<\/p>\n<h1 data-section-id=\"nfolid\" data-start=\"5482\" data-end=\"5494\">Isen\u00e7\u00e3o de responsabilidade<\/h1>\n<p data-start=\"5496\" data-end=\"5860\">RTI-111 is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary applications, therapeutic use, or diagnostic procedures. Users are responsible for complying with all applicable local laws, institutional policies, and laboratory safety regulations.<\/p>","protected":false},"excerpt":{"rendered":"<p><strong data-start=\"5894\" data-end=\"5911\">Nome Do Produto:<\/strong> RTI-111<br data-start=\"5919\" data-end=\"5922\" \/><strong data-start=\"5922\" data-end=\"5944\">Nomes Alternativos:<\/strong> Dichloropane, O-401<br data-start=\"5964\" data-end=\"5967\" \/><strong data-start=\"5967\" data-end=\"5986\">Classe Qu\u00edmica:<\/strong> Phenyltropane Monoamine Transporter Inhibitor<br data-start=\"6202\" data-end=\"6205\" \/><strong data-start=\"6205\" data-end=\"6227\">Categoria de pesquisa:<\/strong> Anal\u00edtico De Refer\u00eancia Padr\u00e3o<\/p>","protected":false},"featured_media":34394,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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Name: RTI-111Alternative Names: Dichloropane, O-401Chemical Class: Phenyltropane Monoamine Transporter InhibitorResearch Category: Analytical Reference Standard","_links":{"self":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product\/34374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/comments?post=34374"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/media\/34394"}],"wp:attachment":[{"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/media?parent=34374"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_brand?post=34374"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_cat?post=34374"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/izchem.com\/pt\/wp-json\/wp\/v2\/product_tag?post=34374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}