Порошок бензилпиперазина (BZP)

About BZP Powder

Benzylpiperazine Powder (BZP) is a recreational drug with euphoriant and stimulant properties. The effects produced by BZP are comparable to those produced by amphetamine.  Also Adverse effects have been reported following its use including acute psychosis, renal toxicity and seizures. Делайте покупки с нами сегодня! Ваш номер 1 онлайн-магазин лекарств 

Pharmacodynamics of BZP Powder

Basically, BZP has been shown to have a mixed mechanism of action, acting on the serotonergic and dopaminergic receptor systems similarly to MDMA. Equally important, BZP has amphetamine-like actions on the serotonin reuptake transporter, which basically increase serotonin concentrations in the extracellular fluids surrounding the cell and thereby increase activation of the surrounding serotonin receptors.

In addition, Benzylpiperazine has a lower potency effect on the noradrenaline reuptake transporter and the dopamine reuptake transporter. BZP has a high affinity action at the alpha2-adrenoreceptor; it is an antagonist at the receptor, like yohimbine, which inhibits negative feedback, causing an increase in released noradrenaline.

Besides, BZP also acts as a non-selective serotonin receptor agonist on a wide variety of serotonin receptors; binding to 5HT_2A receptors may explain its mild hallucinogenic effects at high doses, meanwhile partial agonist or antagonist effects at the 5HT_2B receptors may explain some of BZPs peripheral side effects, However as this receptor is expressed very densely in the gut, and binding to 5HT₃ receptors may explain the common side effect of headaches, as this receptor is known to be involved in the development of migraine headaches.

эффект 

Also important, The effects of BZP are largely similar to amphetamines, with one study finding that former amphetamine addicts were unable to distinguish between dextroamphetamine and BZP administered intravenously. A 2005 study has shown that mixtures of BZP with other piperazine drugs such as TFMPP share certain pharmacodynamic traits with MDMA.

Subjective effects

In fact, Upon ingestion of between 50 mg and 200 mg of BZP, the user may experience any or all of the following:

Initial Effects:

• Feelings of euphoria, wonder, amazement, well-being, energy and elation
• Rapid mood elevation
• Enhanced sociability
• Enhanced appreciation of music
• Increased desire to move, also slight increase in stereotypy
• Skin tingling
• Decreased appetite
• Repetitive thought patterns
• Actual and perceived changes in body temperature
• Mild jaw clenching/bruxism
• Increased heart rate
• Dilation of pupils (see photo)
• тошнота
• промывка
• Mild xerostomia (dry mouth)
• Slight urinary incontinence, often described as “leaking” a small amount of urine after urinating (not due to loss of bladder control)

Later Effects

• Mild headache
• тошнота
• Hangover-like symptoms (common with high doses)
• утомляем
• Indigestion (similar to acid indigestion/heartburn)
• Increased hunger (and sometimes thirst)
• Insomnia
• смущение
• Depression (particularly with frequent/heavy use)

Tolerance

Also Important Research into Benzylpiperazine tolerance is sparse. Anecdotal evidence from online sources claim tolerance to the central action of Benzylpiperazine will develop quickly. Specifically  Due to tiredness associated with the body’s recovery from stimulants, such as BZP, it is uncommon for users to be able to sustain a week-long intake.