UR-144 is a synthetic cannabinoid belonging to the indole-based cannabinoid class. Originally developed by Abbott Laboratories during cannabinoid receptor research, it has become an important analytical reference standard in forensic toxicology, medicinal chemistry, and analytical laboratories. Due to its well-characterized molecular structure and receptor selectivity, UR-144 is frequently utilized in cannabinoid receptor research, analytical method development, forensic investigations, and pharmaceutical research.
UR-144 is supplied strictly for laboratory, analytical, and scientific research purposes only. It is not approved for human or veterinary use.
What is UR-144?
UR-144 is an indole-based synthetic cannabinoid that exhibits high affinity for the cannabinoid CB2 receptor while demonstrating lower affinity for the CB1 receptor. Its receptor profile has made it an important compound in cannabinoid pharmacology and analytical research.
Research laboratories utilize UR-144 as a certified analytical reference material to support analytical method validation, forensic drug screening, metabolite identification, cannabinoid receptor research, and structure–activity relationship (SAR) investigations.
Chemical Structure and Properties
UR-144 possesses several analytical characteristics valuable for laboratory research:
- Indole-based synthetic cannabinoid structure
- Selective cannabinoid receptor ligand
- Well-characterized molecular profile
- High analytical stability
- Excellent chromatographic behavior
- Strong compatibility with LC-MS/MS and GC-MS instrumentation
- Suitable for analytical reference library development
- Reliable forensic identification marker
These characteristics enable reproducible laboratory analyses and accurate compound identification.
Scientific Research Applications
UR-144 is widely employed in:
- Analytical chemistry
- Medicinal chemistry
- Cannabinoid receptor research
- Drug metabolism investigations
- Forensic toxicology
- Toxicological screening
- Pharmaceutical analytical research
- Academic research
- Novel psychoactive substance (NPS) monitoring
- Reference standard development
Analytical Applications
Professional laboratories commonly use UR-144 for:
- LC-MS/MS calibration
- GC-MS identification
- LC-HRMS analysis
- HPLC method validation
- Analytical method development
- Forensic drug screening
- Quality assurance testing
- Metabolite profiling
- Toxicology reference library creation
Its consistent analytical performance makes it valuable for modern forensic and pharmaceutical laboratories.
Pharmacology Research
Researchers investigate UR-144 in studies involving:
- Cannabinoid receptor pharmacology
- CB1 and CB2 receptor characterization
- Structure–activity relationship (SAR) analysis
- Drug metabolism and biotransformation
- Neuropharmacology
- Medicinal chemistry
- Analytical toxicology
- Emerging synthetic cannabinoid research
These investigations contribute to advancements in analytical science, forensic toxicology, and pharmaceutical research.
Why Researchers Choose UR-144
Researchers select UR-144 because it provides:
- High analytical purity
- Well-characterized molecular structure
- Stable chromatographic behavior
- Excellent mass spectrometric response
- Significant forensic relevance
- Reliable analytical reference capabilities
- Broad applicability in toxicology laboratories
Related Research Compounds
Researchers frequently compare UR-144 with related compounds including:
- XLR-11
- A-796,260
- A-834,735
- AB-FUBINACA
- CUMYL-PEGACLONE (SGT-151)
- CUMYL-4CN-BINACA (SGT-78)
- NNE1 (MN-24)
- MDA-19
- JWH-018
- AM-2201
Comparative studies support analytical identification, cannabinoid receptor research, and structure–activity relationship investigations.
Storage and Handling
For optimal laboratory stability:
- Store in airtight laboratory containers.
- Protect from heat, moisture, and direct sunlight.
- Maintain storage in a cool, dry environment.
- Handle using appropriate laboratory personal protective equipment (PPE).
- Follow institutional laboratory safety procedures.
Frequently Asked Questions
What is UR-144?
UR-144 is a synthetic cannabinoid used as an analytical reference standard in forensic toxicology, medicinal chemistry, analytical chemistry, and cannabinoid receptor research.
Which laboratories use UR-144?
It is commonly used by forensic laboratories, toxicology laboratories, pharmaceutical researchers, academic institutions, and analytical chemistry laboratories.
Which analytical techniques are commonly used?
Researchers commonly analyze UR-144 using LC-MS/MS, GC-MS, LC-HRMS, HPLC, and related analytical techniques.
Why is UR-144 valuable in research?
Its well-characterized molecular profile, analytical stability, receptor selectivity, and forensic significance make it valuable for analytical method validation, metabolite identification, cannabinoid receptor studies, and analytical reference development.
Is UR-144 intended only for research?
Yes. UR-144 is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.
Disclaimer
UR-144 is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary applications, therapeutic use, or diagnostic procedures. Users are responsible for complying with all applicable local laws, institutional policies, and laboratory safety regulations.
