Morphine Sulfate
Morphine sulfate is a pain medication of the opiate family that is found naturally in a number of plants and animals, including humans. It acts directly on the central nervous system (CNS) to decrease the feeling of pain. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during labor.
Morphine sulfate can be administered by mouth, by injection into a muscle, by injection under the skin, intravenously, injection into the space around the spinal cord, or rectally. Its maximum effect is reached after about 20 minutes when administered intravenously and 60 minutes when administered by mouth, while the duration of its effect is 3–7 hours. Long-acting formulations of morphine also exist.
How long does morphine stay in your system?
The metabolites of morphine remain in the body even after a person no longer feels the drug’s effects.
People undergoing morphine drug testing should ask about the sensitivity of the test. The more sensitive the test is, the more likely it is to detect morphine. Highly sensitive tests may also produce false positives.
- Blood: Up to 3 days
- Urine: Up to 4 days
- Saliva: Up to 3 days
- Hair: Up to 90 days
Dosage administration
| Adults: | Recommended dose: 10-20 mg (5-10 ml) every 4 hours.
Maximum daily dose: 120 mg per day |
| Pediatric population: | |
| Children 13 to 18 years: | Recommended dose: 5-20 mg (2.5-10 ml) every 4 hours.
Maximum daily dose: 120 mg per day |
| Children 6-12 years: | Recommended dose: 5-10 mg (2.5-5 ml) every 4 hours.
Maximum daily dose: 60 mg per day |
| Children 1-5 years: | Recommended dose 5 mg (2.5 ml) every 4 hours.
Maximum daily dose: 30 mg per day |
| Children under 1 year: | Not recommended. |
Dosage can be increased under medical supervision according to the severity of the pain and the patient’s previous history of analgesic requirements.
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Side effects of Morphine sulfate
- Constipation
- Nausea
- Vomiting
- Stomach pain
- Diarrhea
- Loss of appetite
- Weight loss
- Headache
- Dizziness
- Spinning sensation
- Anxiety
- Flushing (warmth, redness, or tingly feeling)
- Memory problems, or
- Sleep problems (insomnia or strange dreams).
