RTI-111, also known as Dichloropane, is a synthetic phenyltropane research compound originally developed for investigations into monoamine transporter pharmacology. Due to its well-characterized molecular structure and activity at dopamine, norepinephrine, and serotonin transporters, RTI-111 has become an important analytical reference standard in medicinal chemistry, neuropharmacology, forensic toxicology, and analytical laboratories.

Its unique structural characteristics and relevance in neurotransmitter transporter research make RTI-111 valuable for analytical method development, structure–activity relationship (SAR) studies, drug metabolism investigations, and pharmaceutical research.

RTI-111 is supplied strictly for laboratory, analytical, and scientific research purposes only. It is not approved for human or veterinary use.

What is RTI-111 (Dichloropane)?

RTI-111 is a synthetic phenyltropane derivative belonging to the monoamine transporter inhibitor class. It is structurally related to cocaine analogs but was developed primarily as a research compound for studying dopamine, norepinephrine, and serotonin transporter interactions.

Research laboratories utilize RTI-111 as a certified analytical reference material to support transporter research, analytical method validation, forensic screening, metabolite identification, and structure–activity relationship (SAR) investigations.

Estrutura química e Propriedades

RTI-111 possesses several analytical characteristics valuable for laboratory research:

• Phenyltropane core structure
• Dichlorophenyl substituted molecular framework
• Elevada estabilidade analítica
• Comportamento cromatográfico bem definido
• Excelente compatibilidade com instrumentos LC-MS/MS e GC-MS.
• Adequado para o desenvolvimento de bibliotecas de referência analíticas.
• Marcador de identificação forense fiável

Estas características permitem análises laboratoriais reproduzíveis e identificação analítica de elevada fiabilidade.

A Investigação Científica Aplicações

RTI-111 is widely employed in:

• Química analítica
• Química Medicinal
• Investigação em neurofarmacologia
• Investigações sobre o metabolismo dos fármacos
• Toxicologia forense
• Triagem toxicológica
• Investigação analítica farmacêutica
• Pesquisa acadêmica
• investigação sobre transportadores de monoaminas
• Estudos estrutura-atividade (SAR)

Aplicações Analíticas

Professional laboratories commonly use RTI-111 for:

• LC-MS/MS de calibração
• Identificação por GC-MS
• Análise LC-HRMS
• Validação do método HPLC
• Desenvolvimento de métodos analíticos
• rastreio forense de drogas
• Teste de controle de qualidade
• Perfil metabólico
• Criação de biblioteca de referência em toxicologia

O seu desempenho analítico consistente torna-o valioso para os laboratórios forenses e farmacêuticos modernos.

Investigação em Farmacologia

Researchers investigate RTI-111 in studies involving:

• Pesquisa do transportador de dopamina (DAT)
• Investigação sobre o transportador de norepinefrina (NET)
• Serotonin transporter (SERT) research
• Monoamine transporter characterization
• Relação estrutura–atividade (SAR) de análise
• Metabolismo e biotransformação de fármacos
• Química Medicinal
• Toxicologia analítica

Estas investigações contribuem para os avanços na ciência analítica e na investigação farmacêutica.

Why Researchers Choose RTI-111

Researchers select RTI-111 because it provides:

• De alta pureza analítica
• Bem-caracteriza-se a estrutura molecular
• Comportamento cromatográfico estável
• Excelente resposta em espectrometria de massas
• Significant pharmacological research value
• Capacidades de referência analítica fiáveis
• Broad applicability in neuroscience and toxicology laboratories

A Investigação Relacionada Com Compostos

Researchers frequently compare RTI-111 with related compounds including:

• Cocaína
• Tesofensine
• Brasofensine
• NS-2359
• 3,4-DCMP
• O-2390
• RTI-31
• RTI-55
• WIN 35,428
• Methylecgonidine

Comparative studies support analytical identification, transporter research, metabolism studies, and structure–activity relationship investigations.

Armazenamento e Manipulação

Para um óptimo laboratório de estabilidade:

• Loja em hermético recipientes de laboratório.
• Proteger do calor, da humidade e da luz solar direta.
• Conservar em local fresco e seco.
• Manuseie utilizando os equipamentos de proteção individual (EPI) de laboratório adequados.
• Siga institucionais laboratório de procedimentos de segurança.

Perguntas frequentes

What is RTI-111?

RTI-111 (Dichloropane) is a synthetic phenyltropane research compound used as an analytical reference standard in neuropharmacology, forensic toxicology, medicinal chemistry, and analytical chemistry.

Which laboratories use RTI-111?

It is commonly used by forensic laboratories, toxicology laboratories, neuroscience researchers, pharmaceutical researchers, academic institutions, and analytical chemistry laboratories.

Que técnicas analíticas são comummente utilizadas?

Researchers commonly analyze RTI-111 using LC-MS/MS, GC-MS, LC-HRMS, HPLC, and related analytical techniques.

Why is RTI-111 valuable in research?

Its well-characterized molecular profile, transporter research significance, analytical stability, and forensic relevance make it valuable for method validation, metabolite identification, transporter studies, and analytical reference development.

Is RTI-111 intended only for research?

Yes. RTI-111 is supplied exclusively for laboratory, analytical, scientific, and educational research purposes.

Isenção de responsabilidade

RTI-111 is supplied strictly for laboratory, analytical, scientific, and educational research purposes only. It is not intended for human consumption, medical treatment, veterinary applications, therapeutic use, or diagnostic procedures. Users are responsible for complying with all applicable local laws, institutional policies, and laboratory safety regulations.