Купить 5F-КУМИЛ-ПИНАКУ Онлайн
Buy 5F-CUMYL-PINACA Online, the products were analysed by gas chromatography-mass spectrometry.
In some of the e-liquids, an unknown compound was detected, which was identified as the SC 5F-Cumyl-PINACA (1-5-fluorophenyll)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamid by nuclear magnetic resonance analysis.
To investigate the phase I metabolism of this new class of compounds, 5F-Cumyl-PINACA and its non-fluorinated analogue Cumyl-PINACA were incubated with pooled human liver microsomes (pHLM).
Cumyl-PINACA was additionally ingested orally (0.6 mg) by a volunteer in a controlled self-experiment. To assess the relative potency of Cumyl-PINACA, a set of SCswase was characterised using a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
Buy 5F-CUMYL-PINACA Online, the products were analysed by gas chromatography-mass spectrometry.
In some of the e-liquids, an unknown compound was detected, which was identified as the SC 5F-Cumyl-PINACA (1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide) by nuclear magnetic resonance analysis.
To investigate the phase I metabolism of this new class of compounds, 5F-Cumyl-PINACA and its non-fluorinated analogue Cumyl-PINACA were incubated with pooled human liver microsomes (pHLM).
Cumyl-PINACA was additionally ingested orally (0.6 mg) by a volunteer in a controlled self-experiment.
To assess the relative potency of Cumyl-PINAC, a set of SCwasre characterised using a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
To assess the relative potency of Cumyl-PINACA, a set of SCs was characterised using a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
To assess the relative potency of Cumyl-PINACA, a set of SCs was characterised using a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
To assess the relative potency of Cumyl-PINACA, a set of SCswase characterised using a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
To assess the relative potency of Cumyl-PINACA, a set of SCs was ccharacterisedusing a cAMP assay.
Metabolism of 5F-Cumyl-PINACA and Cumyl-PINACA showed similarities with AM-2201 and JWH-018. The main metabolites were formed by hydroxylation at the N-pentyl side chain.
The main metabolites detected in the volunteer’s urine sample were the same as in the pHLM assay.
All SCs tested with the cAMP assay were full agonists at the CB1 receptor. Cumyl-PINACA was the most potent SC among the tested compounds and showed an EC50 value of 0.06 nM.
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